Application of in-line Variable Pathlength Chromatography for High Concentration Oligonucleotide Solutions Scientific Poster
The experiment supports the implementation of in-line variable pathlength chromatography as a viable alternative for in-line variable pathlength spectrophotometer real time integration of high concentration oligonucleotide solutions. When compared to the traditional 1mm fixed pathlength chromatography, the variable pathlength chromatography was able to read real-time high concentration ASO solutions at the target wavelength without going over the readable range.
